Intracardiac Inverse Potential Mapping Using the Method of Fundamental Solutions

• DOI: 10.3389/fphys.2022.873049
• Publication Date: 2022-05-16T06:29:39Z
• Authors: Shu Meng; Nicholas Sunderland; Judit Chamorro-Se...; Laura R. Bear; Nigel A. Lever; Gregory B. Sands; Ian J. LeGrice; Anne M. Gillis; Jichao Zhao; David M. Budgett; Bruce H. Smaill
• Keywords: Cardiac Ablation

Introduction: Atrial fibrillation (AF) is the most prevalent cardiac dysrhythmia and percutaneous catheter ablation widely used to treat it. Panoramic mapping with multi-electrode catheters can identify targets in persistent AF, but limited by poor contact inadequate coverage. Objective: To investigate accuracy of inverse endocardial surface potentials from electrograms sampled noncontact basket catheters. Methods: Our group has developed a computationally efficient 3D technique using meshless method that employs Method Fundamental Solutions (MFS). An in-silico test bed was compare ground-truth corresponding maps reconstructed virtual Ground-truth were derived high-density clinical data computer models. Results: intracardiac potential problem MFS are robust, fast accurate. Endocardial be faithfully recordings real-time if geometry location electrodes relative it known. Larger appropriate electrode density needed resolve complex reentrant atrial rhythms. Conclusion: Real-time panoramic feasible MFS. Significance: Accurate AF appropriately designed