Identification of high-risk patients for development of type B aortic dissection based on novel morphological parameters

• DOI: 10.3389/fphys.2023.1065805
• Publication Date: 2023-02-02T06:40:39Z
• Authors: Da Li; Jiarong Wang; Jichun Zhao; Tiehao Wang; Xiangguo Zeng; Tinghui Zheng; Ding Yuan
• Keywords: Identification

Background: Predicting the development of sporadic type B aortic dissection (TBAD) always remains a difficult issue. This study aimed to identify high-risk patients for TBAD based on morphological parameters. Methods: propensity-score-matched case-control collected and reconstructed computed tomography angiography acute hospital-based control participants without from January 2013 December 2016. Multivariate regression analysis was used calculate adjusted odds ratio (aOR) 95% confidence interval (CI). Discriminant reclassification abilities were compared between our model previously established model. Results: Our included 76 79 (48 cases 48 controls after propensity-score matching). The degree question mark (aOR 1.07, CI 1.04–1.11), brachiocephalic trunk diameter 1.49, 1.20–1.85), angle 0.97, 0.94–0.99), root 1.31, 1.15–1.48), width 1.12, 1.07–1.17) associated with significantly increased risk formation. Similar findings observed in matching sensitivity only including hyperacute patients. A novel prediction aforementioned new showed improved discriminant ability (c-index 0.78 [95% 0.71–0.85] vs. 0.67 0.58–0.75], p = .03), driven by identifying (NRI events 0.16, 0.02–0.30, .02). Conclusion: Morphological predictors, mark, width, diameter, angle, may be at high TBAD.