Effects of dietary pretreated Chinese herbal medicine supplementation on production performance, egg quality, uterine histopathological changes, and antioxidant capacity in late-phase laying hens

• DOI: 10.3389/fphys.2023.1110301
• Publication Date: 2023-01-20T07:04:26Z
• Authors: Ao-Chuan Yu; Min-An Wang; Li Chen; Cheng Long; Yong Guo; Xi-Hui Sheng; Xiang-Guo Wang; Kai Xing; Long-Fei Xiao; He-Min Ni; Jian-Tao Li; Xiao-Long Qi
• Keywords: Haugh unit; Malondialdehyde; Cottonseed meal; Broodstock

Aims: The study aimed to evaluate the effects of pretreated Chinese herbal medicine (PCHM) on egg quality, production performance, histopathological changes in uterus, antiox idant capacity, and antioxidant gene expression late-phase layers. Methods: Jinghong No.1 layers (n = 360, 68 weeks old) were assigned randomly one f our dietary interventions. Each treatment was replicated six times. Repeat 15 chickens per g roup. All birds fed a diet composed corn-soybean meal-based supplemented with 0, 0.2, 0.4, or 0.8% PCHM for 6 weeks. Results: Dietary supplementation had no significant laying rate, feed con sumption, yolk color, shape index. With increasing level Haugh unit linearly increased (P < 0.05). Supplementation weight, compared control can effectively alleviated pathological caused by aging uterus including hemorrhage, many inflammatory cell infiltrations. 0.4% glutathione peroxidase (GSHPx) liver, magnum, plasm considerably, decr ease malondialdehyde (MDA) content, Compared group, mRNA expressions 1 (GPX1), 4 (GPX4), catalase (CAT), nuclear factor E2-related 2 (Nrf2) dramatically rose group In summary, after weight quality hens. Conclusion: antioxidative capacity hens, which could be associated enzymes Nrf2. These findings provide potential using increase performance