Ultrasonic optic disc height combined with the optic nerve sheath diameter as a promising non-invasive marker of elevated intracranial pressure

• DOI: 10.3389/fphys.2023.957758
• Publication Date: 2023-03-10T04:28:45Z
• Authors: Ze-yang Yu; Ying-qi Xing; Cong Li; Si-bo Wang; Xiao-nan Song; Cui-cui Wang; Li-juan Wang
• Keywords: optic nerve sheath diameter; ultrasound; Physiology; intracranial hypertension; optic disc height; intracranial pressure; QP1-981

Background/aim: Patients with elevated intracranial pressure (ICP) tend to have optic disc edema and a thicker nerve sheath diameter (ONSD). However, the cut-off value of height (ODH) for evaluating ICP is not clear. This study was conducted evaluate ultrasonic ODH investigate reliability ONSD ICP. Methods: suspected having increased who underwent lumbar puncture were recruited. measured before puncture. divided according normal We analyzed correlations between ODH, ONSD, points identification determined compared. Results: There total 107 patients recruited this study, 55 52 Both in group higher than [ODH: median 0.81 (range 0.60-1.06) mm vs. 0.40 [0-0.60] mm, p < 0.001; ONSD: 5.01 ± 0.37 4.20 0.38 0.001]. positively correlated (r = 0.613; 0.001) 0.792; 0.001). The values 0.63 4.68 respectively, 73% 84% sensitivity 83% 94% specificity, respectively. combined showed highest under receiver operating characteristic curve 0.965 93% specificity 92%. Conclusion: Ultrasonic may help monitor non-invasively.