Association between olfactory dysfunction and mood disturbances with objective and subjective cognitive deficits in long-COVID

• DOI: 10.3389/fpsyg.2023.1076743
• Publication Date: 2023-02-02T15:12:04Z
• Authors: Tania Llana; Marta Mendez; Sara Garces-Arilla; Vanesa Hidalgo; Magdalena Mendez-...; M.-Carmen Juan
• Keywords: Association (psychology); 2019-20 coronavirus outbreak

Background and purpose The coronavirus disease 2019 (COVID-19) has been associated with olfactory dysfunction. persistent symptoms of anosmia or hyposmia were in previous studies the development memory impairment mood disturbances. We aimed to investigate association between chronicity reported dysfunction subjective objective cognitive performance long-COVID patients explore whether their emotional are related cognition. Methods One hundred twenty-eight participants recruited. Reported symptomatology, complaints, anxiety depression trait-anxiety assessed. Subjective complaints disturbances compared among groups as an acute (AOD), (POD), nonexistent (NOD) symptom. Seventy-six volunteers also participated a face-to-face session assess on tests general function verbal declarative memory. Objective AOD, POD, NOD groups. Results similar groups, but score was lower than those no at any time. Participants’ positively symptoms. relationship depressive symptomatology interacted dysfunction, it only occurred without Depressive negatively delayed performance. months elapsed from diagnosis assessment predicted Anxious immediate ability recall information who did not present phase infection. Conclusion Olfactory infection by COVID-19 is deficits tests, self-reported These findings may contribute further understanding neuropsychological aspects long-COVID.