Assessment of clinical prognosis in autoimmune encephalitis: Girona score

• DOI: 10.3389/fpsyt.2025.1447009
• Publication Date: 2025-01-29T06:58:24Z
• Authors: Gary Álvarez Bravo; Giuseppe Guglielmini; Ana Quiroga Varela; Almudena Boix Lago; Ariadna Gifreu Fr...; Daniele Urso; Giancarlo Logroscino; Lluís Ramió-Torrentà
• Keywords: Autoimmune encephalitis

Background The assessment of clinical prognosis in autoimmune encephalitis: Girona (ACPE-Gi) score is a scale for evaluating the severity acute phase encephalitis (AE) and predicting risk disability at 3 months, measured by modified Rankin (mRS). Methods Patients were strictly diagnosed with AE according to current criteria between 1 January 2009 31 March 2023 University Hospital Dr. Josep Trueta Girona, Catalonia, Spain. ACPE-Gi included 14 items, every item was scored from 0 3, depending on their sum ranging 41. Results grouped patients into three groups: mild (<8; 32%), moderate (8 15; 60%), severe (>15; 8%). We found that third group had higher compared first (p = 0.035). identified mean initial significantly who mRS months level (mRS ≤ 2) 0.023). In addition, autonomic symptoms mental status impairment demonstrated be independent factors predict < 0.05). Conclusions seems reliable comprehensively months. Dysautonomia altered poorer AE.