Longitudinal Vitamin D Deficiency Among Malaysian Pregnant Women and Its Correlation With Neonatal Serum 25-Hydroxyvitamin D Levels

• DOI: 10.3389/fpubh.2021.654292
• Publication Date: 2021-06-29T05:02:04Z
• Authors: Muzaitul Akma Mus...; Hazreen Abdul Majid; Nuguelis Razali; Aswir Abd Rashed; Hussin Muhammad; Abqariyah Yahya
• Keywords: Cord blood; Gee; Longitudinal Study

Objective: This study aimed to investigate the longitudinal relationship between maternal vitamin D concentrations during pregnancy and neonatal at birth. Materials Methods: A prospective cohort of 236 healthy pregnant women from various ethnicity in early (≤20 weeks pregnancy) was followed late (28–40 Maternal serum 25-hydroxyvitamin (25(OH)D) assessed (baseline) pregnancy, while cord 25(OH)D General estimating equations (GEE) were used analyze association levels birth with adjusting for time exposure, weight gain, ethnicity, skin type. Results: The results showed that prevalence deficiency (25(OH)D <50 nmol/L) 89.9, 92.2, 96.1% early, serum, respectively. GEE analysis a trend leads lower blood (RR = 1.17; 95% CI (1.05–1.36); p 0.04). Conclusion: Longitudinal neonates further trial is needed affirm this association.