Trends and disparities in disease burden of age-related macular degeneration from 1990 to 2019: Results from the global burden of disease study 2019

• DOI: 10.3389/fpubh.2023.1138428
• Publication Date: 2023-04-17T05:59:11Z
• Authors: Bo Jiang; Chun Jiang; Jianqing Li; Peirong Lu
• Keywords: trends; Adult; Male; prevalence; Middle Aged; 3. Good health; Global Burden of Disease; Macular Degeneration; Cost of Illness; global burden of disease study; Prevalence; Humans; Female; Public Health; Public aspects of medicine; RA1-1270; age-related macular degeneration; disparities; Retrospective Studies

Objectives This study aims to estimate the trends and disparities in worldwide burden for health of AMD, overall by age, sex, socio-demographic index (SDI), region, nation using prevalence years lived with disability (YLDs) from Global Burden Disease (GBD) 2019. Methods retrospective presents prevalent AMD cases YLDs 1990–2019, as well age-standardized rate (ASPR) YLD (ASYR) AMD. To measure changes over time, estimated annual percentage (EAPCs) rates (ASRs) were analyzed globally, then studied further SDI, nation. We included data 2019 database examine 1990–2019 204 countries territories, demographic information such Results Globally, number increased 3,581,329.17 (95% uncertainty interval [UI], 3,025,619.4–4,188,835.7) 1990 7,792,530 UI, 6,526,081.5–9,159,394.9) 2019, 296,771.93 205,462.8–418,699.82) 564,055.1 392,930.7–789,194.64) The ASPR had a decreased trend an EAPC −0.15 confidence [CI], −0.2 −0.11) ASYR showed −0.71 −0.78 −0.65) during this period. adults 50 age significant increase. significantly higher females than males, overall. ASPRs ASYRs low SDI regions was greater high In addition, increases differed nations, level socio-economic development. Conclusion due 30 directly linked status, geographic location. These findings can not only guide public work but also provide epidemiological basis global strategy formulation regarding challenge.