“COAGULATION”: a mnemonic device for treating coagulation disorders following traumatic brain injury—a narrative-based method in the intensive care unit

• DOI: 10.3389/fpubh.2023.1309094
• Publication Date: 2023-12-06T08:13:20Z
• Authors: Manuel Quintana-Diaz; Pasquale Anania; Raúl Juárez-Vela; Emmanuel Echaniz-...; Clara Isabel Teja...; Pilar Sanchez-Conde; Kapil Nanwani-Nan...; Ainhoa Serrano-Lá...; Pilar Marcos-Neira; María Gero-Escapa; Jorge García-Criado; Daniel Agustín Godoy
• Keywords: Mnemonic; Narrative review; Coagulation Disorder

Introduction Coagulopathy associated with isolated traumatic brain injury (C-iTBI) is a frequent complication poor outcomes, primarily due to its role in the development or progression of haemorrhagic lesions. The independent risk factors for onset are age, severity (TBI), volume fluids administered during resuscitation, and pre-injury use antithrombotic drugs. Although pathophysiology C-iTBI has not been fully elucidated, two distinct stages have identified: an initial hypocoagulable phase that begins within first 24 h, dominated by platelet dysfunction hyperfibrinolysis, followed hypercoagulable state generally starts 72 h after trauma. aim this study was design acronym as mnemonic device provide clinicians auxiliary tool treatment complication. Methods A narrative analysis performed which intensive care physicians were asked list key related C-iTBI. sample comprised 33 respondents. Respondents who physicians, currently working experience coagulopathy excluded. Interviews conducted month until saturated. Each participant single question: Can you identify factor patients TBI? Factors identified respondents then submitted quality check based on published studies proven evidence. Because all had strong support literature, none eliminated. An developed create device. Results conclusion Eleven cerebral computed tomography, oral anticoagulant & antiplatelet use, arterial blood pressure (Hypotension), goal-directed haemostatic therapy, cautiously, low calcium levels, anaemia-transfusion, temperature, international normalised ratio (INR), reversal, normal acid–base status, forming “Coagulation.” This simple device, easy apply anyone facing challenge treating moderate severe TBI daily basis.