Ethnic and racial differences in self-reported symptoms, health status, activity level, and missed work at 3 and 6 months following SARS-CoV-2 infection

• DOI: 10.3389/fpubh.2023.1324636
• Publication Date: 2024-01-30T04:13:12Z
• Authors: Kelli N. O’Laughlin; Robin E. Klabbers; Imtiaz Ebna Mannan; Nicole L. Gentile; Rachel E. Geyer; Zihan Zheng; Huihui Yu; Shu-Xia Li; Kwun C. G. Chan; Erica S. Spatz; Ralph C. Wang; Michelle L’Hommedieu; Robert A. Weinstein; Ian D. Plumb; Michael Gottlieb; Ryan M. Huebinger; Melissa Hagen; Joann G. Elmore; Mandy J. Hill; Morgan Kelly; Samuel McDonald; Kristin L. Rising; Robert M. Rodriguez; Arjun Venkatesh; Ahamed H. Idris; Michelle Santangelo; Katherine Koo; Sharon Saydah; Graham Nichol; Kari A. Stephens
• Keywords: Odds

Introduction Data on ethnic and racial differences in symptoms health-related impacts following SARS-CoV-2 infection are limited. We aimed to estimate the 3 6 months after first infection. Methods Participants included adults with enrolled a prospective multicenter US study between 12/11/2020 7/4/2022 as primary cohort of interest, well SARS-CoV-2-negative account for non-SARS-CoV-2-infection impacts, who completed enrollment 3-month surveys ( N = 3,161; 2,402 SARS-CoV-2-positive, 759 SARS-CoV-2-negative). Marginal odds ratios were estimated using GEE logistic regression individual symptoms, health status, activity level, missed work COVID-19 illness, comparing each ethnicity or race referent group (non-Hispanic white), adjusting demographic factors, social determinants health, substance use, pre-existing conditions, vaccination survey time point, interactions status point. Results Following infection, majority similar over groups. At months, Hispanic participants more likely than non-Hispanic report fair/poor (OR: 1.94; 95%CI: 1.36–2.78) reduced (somewhat less, OR: 1.47; 1.06–2.02; much 2.23; 1.38–3.61). by not present. Other/Multiple white 1.90; 95% CI: 1.25–2.88), 1.72; 1.21–2.46; 2.08; 1.18–3.65). Asian 1.88; 1.13–3.12); Black reported (OR, 2.83; 1.60–5.00); 1.83; 1.10–3.05), 1.60; 1.02–2.51; 2.49; 1.40–4.44), 2.25; 1.27–3.98). Discussion Awareness outcomes may inform clinical public efforts advance equity long-term outcomes.