Metagenomic probing toward an atlas of the taxonomic and metabolic foundations of the global ocean genome

• DOI: 10.3389/fsci.2023.1038696
• Publication Date: 2024-01-16T10:12:38Z
• Authors: Elisa Laiolo; Intikhab Alam; Mahmut Uludag; Tahira Jamil; Susana Agusti; Takashi Gojobori; Silvia G. Acinas; Josep M. Gasol; Carlos M. Duarte
• Keywords: Biome; Biogeochemical Cycle

The global ocean genome (the pool of genes in marine organisms and the functional information they encode) is a major, untapped resource for science society with growing range biotechnology applications sectors such as biomedicine, energy, food. Shotgun sequencing metagenomics can now be used to catalog diversity microbial life explore its potential, but has been limited by sample coverage, access suitable platforms, computational capacity. Here we provide novel synthesis based on analysis 2,102 sampled metagenomes, gene assembly annotation via KAUST Metagenome Analysis Platform (KMAP) Global Ocean Gene Catalog 1.0 containing 308.6 million clusters. Taxonomically, report distribution across tree different basins depth zone biomes. Functionally, map relationship protein families biogeochemical processes, including major metabolic pathways that process three elements play fundamental roles cycles are relevant climate change. These data extend our understanding complex, dynamic nature microbiome capabilities. Further research critical importance both unlock potential understand predict effects human-induced changes, pollution hypothesis-driven should target under-sampled deep sea benthic communities using enhanced metagenomic methods, better ecosystem functioning. Investment necessary capacity essential, intellectual property frameworks.