Effect of maternal lactoferrin supplementation on iron contents and anti-oxidant capacity in Dahe black Pig neonates

• DOI: 10.3389/fvets.2022.1034084
• Publication Date: 2022-10-31T05:53:22Z
• Authors: Chunyong Zhang; Cenxi Li; Xiaokun Xing; Peng Ji; Meiquan Li; Hongbin Pan; Rongfu Guo; Qingcong An
• Keywords: Lactoferrin; Total iron-binding capacity

Iron levels are closely related to animals' growth performance and anti-oxidant function. Lactoferrin (LF) is an iron-binding glycoprotein, which can promote the absorption of iron regulate immune This study aimed clarify effect maternal LF supplementation on metabolism Dahe piglets. Sixty sows (Dahe black, parity 3-4, no significant differences in body weight) were randomly assigned five groups: control (basal diet with supplementation), supplemented 100 (LF1 group), 200 (LF2 or 300 (LF3 group) mg LF/kg basal diet, (Fe-Gly Fe/kg as ferrous glycine (Fe-Gly). The serum parameters neonatal piglets determined. contents, gene expression levels, Fe-acquisition genes detected liver, heart, spleen, other organs. results indicated that (1) LF3 group had highest colostrum contents (P < 0.05). significantly promoted stores lung compared Fe-Gly. (2) increased glutathione peroxidase (GSH-Px) total superoxide dismutase (T-SOD) activities sows. Compared groups, capacity (T-AOC) activity LF2 groups (3) piglet GSH-Px, T-SOD, T-AOC (4) Gene SOD duodenum jejunum higher than Fe-Gly 0.05), while liver heart lower (5) hepcidin In conclusion, showed remarkable effects storage piglets, exhibited strong antioxidant activities, it helpful prevent occurrence deficiency, improves function animals.