Pregnancy Loss and Risk of All-Cause Mortality in Chinese Women: Findings From the China Kadoorie Biobank

• DOI: 10.3389/ijph.2023.1605429
• Publication Date: 2023-04-14T04:11:14Z
• Authors: Li Jiang; Sha Huang; Jia Yi Hee; Yiqian Xin; Siyu Zou; Kun Tang
• Keywords: Adult; China; Public Health Archive; East Asian People; Abortion, Induced; Middle Aged; Stillbirth; maternal health; 3. Good health; Abortion, Spontaneous; spontaneous abortion; Pregnancy; Cardiovascular Diseases; Risk Factors; all-cause mortality; Humans; stillbirth; Female; pregnancy loss; Public aspects of medicine; RA1-1270; Aged; Biological Specimen Banks

Objectives: Pregnancy loss is a common obstetric complication that may be associated with maternal mortality. However, evidence sparse and inconsistent. This study aims to investigate the association between pregnancy risk of all-cause mortality among Chinese women. Methods: Data on 299,582 women aged 30-79 years old from China Kadoorie Biobank were used. Cox proportional hazard regression was conducted occurrence Results: Two or more losses long-term (adjusted ratio (aHR) 1.10, 95% CI: 1.03-1.18). Specifically, than one spontaneous abortion stillbirth (aHR 1.01-1.21 1.14, 1.04-1.25, respectively). When stratified by presence cardiovascular disease diabetes, as well age at baseline, two in ≥50 diagnosed 1.32, 1.18-1.48) diabetes 1.30, 1.06-1.60) Conclusion: Recurrent loss, particular abortions stillbirths increased The associations recurrent pronounced baseline.