Antibacterial Aerogels-Based Membranes by Customized Colloidal Functionalization of TEMPO-Oxidized Cellulose Nanofibers Incorporating CuO

• DOI: 10.3390/bioengineering10111312
• Publication Date: 2023-11-14T16:03:45Z
• Authors: Elena Usala; Eduardo Espinosa; Wasim El Arfaoui; Ramón Morcillo-Ma...; Begoña Ferrari; Zoilo González
• Keywords: Nanocellulose; Surface Modification

An innovative colloidal approach is proposed here to carry out the customized functionalization of TEMPO-Oxidized Cellulose Nanofibers (CNF) incorporating non-noble inorganic nanoparticles. A heterocoagulation process applied between delignified CNF and as-synthetized CuO nanoparticles (CuO NPs) formulate mixtures which are used in preparation aerogels with antibacterial effect, could be manufacture membranes, filters, foams, etc. The involved components formulated blending, NPs, were individually obtained by using a biorefinery strategy for agricultural waste valorization, together an optimized chemical precipitation, assisted ultrasounds. optimization synthesis parameters NPs has avoided presence undesirable species, usually requires later thermal treatment associated costs. aerogels-based structure, conventional freeze-drying, acted as 3D support providing good dispersion within cross-linked structure nanocellulose facilitating direct contact phase against microorganisms. All samples showed positive response Escherichia coli Staphylococcus aureus. increase aerogels, measured agar disk diffusion test, been observed incorporated, obtaining width antimicrobial "halo" (nwhalo) from 0 0.6 0.35 S. aureus E. coli, respectively. Furthermore, have able deactivate less than 5 h when assays analyzed broth dilution method. From CNF-50CuO samples, overlap nanoparticle effect produced decrease kinetic.