Systemic Inflammatory Response Index and Futile Recanalization in Patients with Ischemic Stroke Undergoing Endovascular Treatment

• DOI: 10.3390/brainsci11091164
• Publication Date: 2021-09-01T01:59:45Z
• Authors: Simona Lattanzi; Davide Norata; Afshin A. Divani; Mario Di Napoli; Serena Broggi; Chiara Rocchi; Santiago Ortega-G...; Gelsomina Mansueto; Mauro Silvestrini
• Keywords: Stroke

Futile recanalization remains a significant challenge for endovascular treatment (EVT) of acute ischemic stroke (AIS). The inflammatory response that occurs after cerebral infarct plays central role in pathobiology can influence the outcome procedure. aim this study was to evaluate relationship between systemic index (SIRI) and futile patients with AIS. We retrospectively identified consecutive due proximal arterial occlusion anterior circulation, who were treated EVT achieved near-complete or complete recanalization. Absolute neutrophil count (ANC), absolute monocyte (AMC), lymphocyte (ALC) collected from admission blood work calculate SIRI as ANC × AMC/ALC. recanalization, defined poor functional status [modified Rankin scale (mRS) score ≥ 3] at 3 months despite A total 184 included. observed 110 (59.8%) patients. Older (odds ratio (OR) = 1.07, 95% confidence interval (CI): 1.04–1.10, p < 0.001), higher National Institutes Health (OR 1.10, CI: 1.02–1.19, 0.013), 1.08, 1.01–1.17, 0.028) increased risk