Theta and Gamma Activity Differences in Obsessive–Compulsive Disorder and Panic Disorder: Insights from Resting-State EEG with eLORETA

• DOI: 10.3390/brainsci13101440
• Publication Date: 2023-10-10T07:24:55Z
• Authors: Ilju Lee; Kyoung Min Kim; Myung Ho Lim
• Keywords: Superior frontal gyrus

Background: Obsessive-compulsive disorder (OCD) and panic (PD) are debilitating psychiatric conditions, yet their underlying neurobiological differences remain underexplored. This study aimed to directly compare resting-state EEGs in patients with OCD PD, without a healthy control group, using the eLORETA method. Methods: We collected retrospective EEG data from 24 22 PD who were hospitalized due significant impairment daily life functions. was used analyze data. Results: Heightened theta activity observed anterior cingulate cortex (ACC) of compared (PD vs. OCD, t = -2.168, p < 0.05). Conversely, higher gamma found medial frontal gyrus (MFG) paracentral lobule (PCL) 2.173, Conclusions: Our findings highlight between patients. Specifically, increased ACC for elevated MFG PCL offer preliminary insights into neural mechanisms these disorders. Further studies essential validate results delve deeper underpinnings.