Sonographic Assessment of Complex Ultrasound Morphology Adnexal Tumors in Pregnant Women with the Use of IOTA Simple Rules Risk and ADNEX Scoring Systems

• DOI: 10.3390/diagnostics11030414
• Publication Date: 2021-03-01T01:43:32Z
• Authors: Artur Czekierdowski; Norbert Stachowicz; Agata Smoleń; Tomasz Kluz; Tomasz Łoziński; Andrzej Miturski; Janusz Kraczkowski
• Keywords: Ovarian tumor

Background: To evaluate the accuracy of subjective assessment (SA), International Ovarian Tumor Analysis (IOTA) group Simple Rules Risk (SRR) and Assessment Different NEoplasias in adneXa (ADNEX) model for preoperative differentiation adnexal masses pregnant women. Methods: The study population comprised 36 women (median age: 28.5 years old, range: 20–42 old) with a mean gestation age 13.5 (range: 8–31) weeks at diagnosis. Tumors were prospectively classified by local sonographers as probably benign or malignant using SA. Final tumor histological diagnosis was used reference standard all cases. Logistic regression SRR ADNEX models to obtain risk score every case. Serum CA125 human epidydimis protein 4 (HE4) concentrations also retrieved Malignancy Algorithm (ROMA) value calculated. calculated predictive values included positive negative likelihood ratios ultrasound biochemical tests. Results: histology confirmed 27 9 (including 2 borderline) masses. highest sensitivity (89%) specificity (70%) found assessment. Although no malignancy criteria (sensitivity = 100%), this scoring system only 37%. At cut-off level >20%, had 78% 70%. levels CA125, HE4 ROMA correctly identified tumors 67%, 25% 25%, respectively. Corresponding specificities 72%, 100% 100%, SA (LR+ 3.0 LR− 0.16, respectively). Overall diagnostic methods similar 70–75%) except (53%). Conclusion: Subjective remains best method complex prenatal For less experienced sonographers, both systems may be characterization such tumors, while serum markers HE4, along algorithm appear accurate.