Issues with Cefiderocol Testing: Comparing Commercial Methods to Broth Microdilution in Iron-Depleted Medium—Analyses of the Performances, ATU, and Trailing Effect According to EUCAST Initial and Revised Interpretation Criteria

• DOI: 10.3390/diagnostics14202318
• Publication Date: 2024-10-18T09:03:49Z
• Authors: Stefano Stracquad...; Alice Nicolosi; Andrea Marino; Maddalena Calvo; Stefania Stefani
• Keywords: Acinetobacter baumannii; Broth microdilution

The rise of multi-drug-resistant Gram-negative bacteria necessitates the development new antimicrobial agents. Cefiderocol shows promising activity by exploiting bacterial iron transport systems to penetrate outer membranes resistant pathogens.