Subtyping Cryptosporidium ryanae: A Common Pathogen in Bovine Animals

• DOI: 10.3390/microorganisms8081107
• Publication Date: 2020-07-24T13:06:09Z
• Authors: Xin Yang; Ni Huang; Wen Jiang; Xinrui Wang; Na Li; Yaqiong Guo; Martin Kváč; Yaoyu Feng; Lihua Xiao
• Keywords: Subtyping; Furin; Molecular Epidemiology

Cryptosporidium ryanae is one of the most common species for cryptosporidiosis in cattle. However, little known genetic characteristics C. due to lack subtyping tools. In present study, 60-kDa glycoprotein (gp60) gene was identified whole genome sequence data and analyzed using bioinformatics The protein it encodes had some typical GP60 proteins, with a signal peptide, furin cleavage site, glycosylphosphatidylinositol anchor at C terminus protein, numerous O-glycosylation sites. used development tool, which characterizing from 110 specimens dairy cattle, 2 beef 6 yaks, 4 water buffaloes China. Altogether, 17 subtypes 8 subtype families were recognized, namely XXIa XXIh. Possible host adaption within this species, reflected by unique occurrence XXIa, XXIc, XXIh buffaloes, respectively. Some geographical differences detected distribution cattle; southern China showed higher diversity than northern China, family only seen cattle eastern gp60-based tool should be useful molecular epidemiological studies transmission ryanae.