Profile and Content of Phenolic Compounds in Leaves, Flowers, Roots, and Stalks of Sanguisorba officinalis L. Determined with the LC-DAD-ESI-QTOF-MS/MS Analysis and Their In Vitro Antioxidant, Antidiabetic, Antiproliferative Potency

• DOI: 10.3390/ph13080191
• Publication Date: 2020-08-12T13:14:49Z
• Authors: Sabina Lachowicz; Jan Oszmiański; Andrzej Rapak; Ireneusz Ochmian
• Keywords: RS1-441; 0303 health sciences; 03 medical and health sciences; bioactive compounds; Pharmacy and materia medica; morphological parts; medical plant; R; in vitro biological activity; Medicine; Article

The aim of this study was to accurately determine the profile polyphenols using highly sensitive LC-DAD-ESI-QTOF-MS/MS technique and in vitro antioxidant activity, ability inhibition α-amylase, α-glucoamylase, pancreatic lipase antiproliferative activity leaves, flowers, roots, stalks medical plant Sanguisorba officinalis L. results analysis morphological parts indicated presence 130 polyphenols, including 62 that were detected S. for first time. prevailing group tannins, with contents ranging from 66.4% total flowers 43.3% stalks. highest content identified reached 14,444.97 mg/100 g d.b., while lowest noted 4606.33 d.b. In turn, values antiradical reducing capacities determined leaves 6.63 0.30 mmol TE/g d.b, respectively. a high inhibit activities α-amylase α-glucoamylase demonstrated addition, showed most effective properties ductal adenocarcinoma, colorectal bladder cancer, T-cell leukemia cells, whereas weakest Thus, best dietetic material be used when composing functional foods L., roots equally valuable materials.