The Effects of a 6-Month Omega Fatty Acid and Antioxidant Vitamin Supplementation on Functional Capacity and Cognitive Function in Older Adults with Cognitive Impairment

• DOI: 10.3390/proceedings2019025036
• Publication Date: 2019-09-10T14:52:26Z
• Authors: Pinelopi S. Stavr...; Eleni Andreou; George Aphamis; Melina Ioannou; Marios Pantzaris; Christoforos D. G...
• Keywords: Cognitive test

Aim: Aging is associated with declines in functional capacity and cognitive function. The aim of the present study was to examine, for first time, effects a high-dose omega-3 omega-6 fatty acid supplementation, combination antioxidant vitamins, on function older adults impairment, over 6-month period randomized, double-blind, placebo-controlled design. Material & Method: Thirty-six impairment (aged 79.3 ± 7.6 yrs, 22 females) were randomized receive either formula containing mixture acids vitamins or placebo six months. Participants completed assessments capacity, function, various aspects quality life at baseline following three months supplementation. Functional evaluated using two sit-to-stand tests (STS-5, STS-60), timed-up-and-go test (TUG), 6-min walk (6MWT), handgrip strength test. Cognitive through Addenbrooke's Examination Revised (ACE-R) Mini Mental State (MMSE), whilst health-related life, sleep quality, daily sleepiness, fatigue assessed by specific questionnaires. A linear mixed model random effect participant used evaluate differences dependent variables between supplementation groups throughout it adjusted age education participants. Results: significant interaction time found (6MWT STS-60; p = 0.028 0.032, respectively), (ACER MMSE; < 0.001 0.011, (p 0.001), physical health component 0.007), sleepiness showing favorable improvement participants receiving nutritional supplement. Conclusions: results showed that omega vitamin improves impairment. Thus, this novel approach appears promising reducing decline frailty elderly.