Comparison of Safety and Efficacy of Potassium Hydroxide versus Combination of Salicylic and Lactic Acid for Molluscum Contagiosum

• DOI: 10.35787/jimdc.v8i3.418
• Publication Date: 2019-09-29T15:06:25Z
• Authors: Durre-Shehwar Ar...; Sumaira Abdullah; Qurat-ul Ain Zia; Syed Afaq Ahmed; Hamid Ali
• Keywords: Molluscum contagiosum; Erythema; Potassium hydroxide

Background: Molluscum contagiosum (MC) is a contagious cutaneous infection caused by MC virus, affecting mainly the pediatric population. It characterized flesh-colored umbilicated papules occurring on skin surface. Potassium hydroxide (KOH) and salicylic acid plus lactic combination being keratolytic agents, are effective treatment options. The objective of study was to compare efficacy safety 10% KOH solution versus acid/ in treating population.
 Material Methods: A total 80 children (age range 1-13 years) with lesions were selected from Dermatology Out-Patient Department, randomly allocated into two groups lottery method. Group given topical group B Salicylic Lactic preparations for application. Patients followed after weeks see regression size lesion, development any side-effects. Final visit scheduled at 6 weeks. Statistical analysis carried out using SPSS (version 16) p value less than 0.05 considered as statistically significant.
 Results: (n = 80) equally divided (treated KOH) acid). After weeks, complete remission virus seen 29 (72.5%) patients 34 (85%) B. There 12 (30%) who developed local irritation 4 (10%) erythema None had such side effects.
 Conclusion: acids population, however it associated effects erythema.