Procalcitonin as a Predictor of Acute Kidney Injury Following Cardiopulmonary Bypass

• DOI: 10.36347/sasjs.2025.v11i02.008
• Publication Date: 2025-02-15T06:32:56Z
• Authors: Dr. Golam Mursalin; Dr. Mehdi Rafique...; Dr. Md. Alauddin; Dr. Kashfia Mehrin; Dr. Debasish Das; Dr. Md. Rezwanul ...
• Keywords: Procalcitonin

Background: Renal dysfunction following cardiac surgery involving cardiopulmonary bypass is associated with considerable morbidity and mortality. Procalcitonin has demonstrated effectiveness as a biomarker for guiding the initiation duration of antibiotic therapy in patients admitted to intensive care units. This study aimed assess procalcitonin predictor acute kidney injury bypass. Methods: prospective observational was conducted at Department Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh from January 2021 December 2023. A total 40 who underwent elective were enrolled purposively. Data analyzed using SPSS version 23.0. Results: Postoperatively, 37.5% experienced (AKI), 86.7% classified stage 1 13.3% 2 AKI. significant association observed between development AKI elevated postoperative levels (p < 0.05), indicating that higher correlate an increased risk Receiver Operating Characteristic (ROC) analysis diagnosis revealed Area Under Curve (AUC) 0.860 (95% CI: 0.725–0.995). cutoff value ≥4 ng/ml 80% sensitivity 92% specificity. Conclusion: The serum on 1st post-operative day can predict undergoing