Effect of D-galactose on Weight Gain in Animal Model of Aging

• DOI: 10.36347/sjavs.2021.v08i06.001
• Publication Date: 2022-06-22T06:16:12Z
• Authors: Dwi Sunu Datrianto; Yonathan Alvin Ma...; Topas Wicaksono P...; Surya Agus Prihatno; Teguh Budipitojo; Yosua Kristian Adi
• Keywords: 0303 health sciences; 03 medical and health sciences; 3. Good health

D-galactose is widely used as an inducing reagent for animal models of aging. The aging model by induction has similarities with natural old. In this study, we described the effect administration in rats against their body weight. Thirty healthy male aged 2 months were divided into groups. Control group was treated aqua sterile placebo, while 3 mg/kg BW D-Galactose orally every day 6 weeks. both groups measured using digital weigher week. data analyzed descriptively average weight (g) each week and statistically gain (%) after weeks t-test. control from week-0 until week-6 119± 16.24; 144± 20.24; 160± 27.37; 170± 29.08; 179± 32.79; 197± 32.37; 208± 32.07, 129± 13.92; 151± 15.94; 164± 24.63; 173± 25.37; 182± 27.15; 192± 25.55; 25.55. Statistical analysis t-test showed that there a significant difference (p<0.05). 75.59%±21.19% 53.76%±21.79%, respectively. could decrease rat