Effects of different stent configurations on shunt failure and hepatic encephalopathy after transjugular intrahepatic portosystemic shunt

• DOI: 10.3760/cma.j.issn.0254-1432.2017.10.005
• Publication Date: 2017-10-15
• Authors: Weizhi Li; Fuquan Ma; Shuzhen Kong; Peijie Li; Mengying Liu; Jin Huang; Bo Ram Yang
• Keywords: Hepatic Encephalopathy; Portography; Portosystemic shunt

Objective To compare the effects of different stent configurations on shunt failure, hepatic encephalopathy, and myelopathy after transjugular intrahepatic portosystemic (TIPS).

Methods From March 2014 to June 2015, clinical data 73 hospitalized patients who met inclusion exclusion criteria, underwent TIPS for upper gastrointestinal hemorrhage caused by cirrhotic portal hypertension were retrospectively analyzed. According configuration during operation, divided into simple coated group (hepatic vein, vein parenchyma stent, 23 cases), simulated Viatorr plus bare 27 cases) combined cases). Patients followed up one year, incidences encephalopathy within year three groups compared. Chi-square test, Fisher exact probability method variance analysis performed comparison among groups. Cox regression was used difference in imbalance variables incidence outcome events groups.

Results The pressure gradient group, decreased from (22.15±4.52), (23.01±5.48) (21.13±4.49) mmHg (1 mmHg=0.133 kPa) (9.15±2.94), (11.20±3.27) (8.75+ 4.06) respectively. Before differences venous statistically significant (t=10.488, 7.188 7.850, all P 0.05). The results showed that relative ratio values (95% confidence interval) postoperative compared with 2.901 (1.279 6.584) 2.735 (1.123 6.658), (both During one-year follow-up, patients, two died, other group. survival rate 97.3%.

Conclusions One failure are similar between One is which both lower than stent. low, its association remains be further investigated.

Key words: Liver cirrhosis; Hypertension, portal; Portasystemic shunt, intrahepatic; Shunt failure; Hepatic