[Effects of different computed high b-values on diffusion weighted imaging scores in Prostate Imaging Reporting and Data System version 2 of prostate cancer in peripheral zone].

• DOI: 10.3760/cma.j.issn.0376-2491.2017.43.009
• Publication Date: 2017-11-21
• Authors: Wei Wang; Zhijiang Shao; Johnathan Zeng; Dijun Wu; G-l Wang; P J Wang
• Keywords: Diffusion imaging

Objective: To determine the effects of different computed high b-value on diffusion weighted imaging (DWI) scores in Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) prostate cancer peripheral zone. Methods: A retrospective study 104 cases zone was conducted, all patients were histopathologically confirmed by transrectal ultrasound guided saturation biopsy or radical prostatectomy Tongji Hospital University from January 2012 to December 2015.All MRI examinations performed using a 3.0T Siemens Verio scanner.The protocol consisted high-resolution axial sagittal T(2) (T(2)WI), acquired (aDWI) with b=0, 50, 1 000 s/mm(2) dynamic contrast-enhanced (DCE) scans.Computed (cDWI) images b=1 000, 400, processed Matlab.These three groups cDWI analyzed according PI-RADS v2 criteria, signal intensity ratio (SIR) lesions independent t test one-way ANOVA each group. Results: The numbers DWI score 5 similar among groups.Nine (33.3%) 27 3 upgraded 4 when rose 400 s/mm(2).The ratios SIR those unchanged 1.86±0.21 1.61±0.27 2.18±0.26 1.75±0.30, respectively (t=2.486, t=3.671, both P<0.05). In these 9 who 4, SIRs lesion significantly between (F=10.907, 33.768, 8.043, P<0.05), their increased rising b-value. Conclusions: (b≥1 s/mm(2)) mainly affects 3, but would not change neither nor cases. For zone, is probably more scoring value than s/mm(2).目的： 探讨不同计算化高扩散敏感系数(b值)对外周带前列腺癌第二版前列腺影像和数据报告系统(PI-RADS v2)中弥散加权成像(DWI)评分的影响。 方法： 回顾性分析2012年1月至2015年12月在同济大学附属同济医院经直肠超声引导下前列腺饱和穿刺活检或前列腺根治术后病理证实外周带前列腺癌104例患者的临床资料。所有患者均采用Siemens MRI扫描，成像序列包括横断位、矢状位高分辨T(2)加权成像(T(2)WI)，b值＝0、50、1 s/mm(2)横断位弥散加权成像(aDWI)及动态对比增强(DCE)扫描，通过Matlab后处理计算化合成b＝1 000、1 400、2 s/mm(2)的DWI图像(cDWI)。依据PI-RADS v2评分标准对b＝1 s/mm(2)的三组cDWI资料进行评分，并对各组病例的病灶信号强度比(SIR)进行独立样本t检验及单因素方差分析。 结果： 三组cDWI中DWI评分2、5分的病例数无差别，27例b＝1 DWI评分3分的病例中有9例(33.3%)在b＝1 s/mm(2)及b＝2 s/mm(2)时DWI评分均升高到4分。升高至DWI评分4分的病例与仍为DWI评分3分的病例间的病灶SIR在b＝1 s/mm(2)时的比值分别为1.86±0.21比1.61±0.27、2.18±0.26比1.75±0.30，两组间SIR差异均有统计学意义(t＝2.486、3.671，均P<0.05)。升高至DWI评分4分的9例病例的病灶SIR在b＝1 s/mm(2)时两两之间差异均有统计学意义(F＝10.907、33.768、8.043，均P<0.05)，且病灶SIR均随b值的升高而增大。 结论： b≥1 s/mm(2)的高b值主要影响DWI评分3分的病例，但b＝2 s/mm(2)不改变b＝1 s/mm(2)时的DWI评分，b＝1 s/mm(2)可能更适用于外周带前列腺癌的PI-RADS v2中DWI评分。.