Dosimetric evaluation for head and neck cancer patients treated with helical TomoTherapy

• DOI: 10.3760/cma.j.issn.1004-4221.2014.06.016
• Publication Date: 2014-11-15
• Authors: Yongqian Zhang; Fuli Zhang; Yadi Wang; Junmao Gao; Weidong Xu; Huayong Jiang; Bo Yao
• Keywords: Tomotherapy; Image registration

Objective To compare the differences between planning dose and actual of targets organs at risk (OAR) for head neck cancer patients with helical tomotherapy (HT).Methods 12 HT were enrolled in this study.Prior to each treatment fraction,an MVCT scan was performed.The images first fraction week since second chosen,and distributions recalculated on Planned Adaptive application HT,which fraction.Each single distribution corresponding CT image sent commercial software (MIM5.5),and deformable registration performed images,and sum acquired.Dose OAR initial plan (Plan-1) (Plan-2) compared.Results There no significant Plan-1 plan-2 D2,D50 GTV (P =0.07,0.07) D2 PTV =0.08).D95,D98 D100 Plan-2 lower than Plan-l,with 2.1％,2.7％ 5.6％ =0.02,0.02,0.02),respectively.D50,D95,D98 Plan-1,with 0.8％,1.9％,3.9％ 13.5％ =0.01,0.00,0.00,0.01),respectively.Dose spinal cordwas higher Plan-1,increasing by an Dmax 1.2％ =0.04).Conclusions In radiotherapy dose.Max cord,however,was plan.For who have a anatomic change,in order achieve best therapeutic effect,modification appropriate time is essential.

Key words: Head neoplasms/helical tomotherapy; Image-guided; Deformable registration; Dosimetry