Clinical outcomes of individualized catheter ablation strategy in patients with paroxysmal atrial fibrillation

• DOI: 10.3760/cma.j.issn.1007-6638.2015.02.014
• Publication Date: 2015-04-28
• Authors: Deyan Yang; Hua Deng; Peng Gao; Kangan Cheng; Taibo Chen; Zhongwei Cheng
• Keywords: Venae cavae; Premature atrial contraction

Objective To investigate the clinical outcomes of individualized catheter ablation strategy targeting trigger potentials in patients with paroxysmal atrial fibrillation (PAF).

Methods Data PAF for first were analyzed retrospectively. Repeated 12-Leads electrocardiography (ECG) and/or 24 hours ambulatory (Holter) ECG performed before procedure. Triggers fibrillations determined by P wave morphology premature contraction (PAC) initiating and confirmed if earliest could be recorded deca-polar ring (LASSO) from prejudged pulmonary veins (PV) or venae cava during spontaneous isoprenaline induced PAF. A simplified was to identified triggers resulting (individualized group), i.e. circumferential only on same side containing potentials. Other without underwent standard isolation (CPVI) (standard group) as control. All followed-up clinic at an interval every 3 months.

Results Eighty-one (59.2±11.3 years old) enrolled. Individualized 23 (11 females). The left PV 13 cases, right 6 superior 2 both 1 case, case. Procedure fluoroscopy time (72.6±10.2) minutes vs. (97.6±24.0) (P=0.001) (21.7±4.2) (28.3±10.0) (P=0.029), respectively. During a mean follow-up period (495.7±187.8) days, 16 (69.6%) group 30 (51.7%) free arrhythmias (P=0.167) after procedure.

Conclusion The under guidance surface intracardiac electrogram might least equivalent CPVI significantly shorter procedure time.

Key words: Atrial fibrillation; Radiofrequency