Related factors of mortality for patients with diabetic ketoacidosis

• DOI: 10.3760/cma.j.issn.1674-6090.2017.06.007
• Publication Date: 2017-12-25
• Authors: Caojie Chen; Chi Xu
• Keywords: Diabetic ketoacidosis; Ketoacidosis; Univariate analysis; Diabetic coma

Objective To study the factors related to mortality of diabetic ketoacidosis (DKA) .

Methods From Jan. 2011 Dec. 2015, 109 hospitalized patients with were selected as subjects, which included 39 cases type 1 diabetes and 70 2 diabetes. DKA aging from 20 45 years, including males females, average age 42. The death group had 17 cases, 6 11 females 56. survival 92 33 59 41. Age, 12 h blood glucose, sex, disturbance consciousness, BMI, hypernatremia, shock, hyperlipidemia, insulin dosage, hyperkalemia, fever, mellitus, family history diabetes, infection combined use basic disease sorted out analyzed.

Results Among DKA, died rate was 15.6%. causes deaths acute myocardial infarction in 4 left ventricular dysfunction 5 3 case cardiac arrest, renal insufficiency case, cerebrovascular case. Univariate regression analysis showed that age, 12h infection, underlying diseases may be risk for poor prognosis. Multivariate logistic (OR=2.954, 95% CI: 3.081-8.261, P=0.002) , glucose <16.7 mmol/L (OR=1.592, 1.915-4.920, P=0.006) (OR=2.621, 1.814-3.945, P=0.030) (OR=2.913, 3.014-9.405, P=0.000) independent mortality.

Conclusion By stratifying patients, prognosis can improved rationally effectively.

Key words: Endocrine disease; Diabetic ketoacidosis; Diabetes; Mortality