Changes of meibomian gland function and the stability of tear film after long-term wearing orthokeratolog

• DOI: 10.3760/cma.j.issn.2095-0160.2018.06.013
• Publication Date: 2018-06-10
• Authors: Yinghui Shi; Jingzhi Zhang; Yangguang Li; Huimin Zhou; Ting Liu
• Keywords: Meibomian gland; Schirmer test

Objective This study was to observe the meibomian gland scores, miss rate of meibomian, break-up time tear film (BUT) changes after long-term wearing orthokeratolog, and evaluate orthokeratolog impact on function stability film.

Methods A prospective case-controlled performed.Fifty patients 98 eyes with myopia were enrolled.According correction mode, divided into control group (24 cases) experimental (overnight treatment) (26 cases). All subjects underwent examinations sequentially as follows: evaluation ocular surface disease symptoms using Ocular Surface Disease Index(OSDI), lid margin examination by slit lamp microscrope, infrared photography BUT.All measurements repeated at 3 months, 6 24-months follow-up visit.All signed informed consent before examination.

Results After orthok-contact lens for 24 score 4.54±1.10 2.29±0.75 in group, respectively, difference statistically significant (P 0.05).

Conclusions Long-term has negetive effects film.

Key words: Myopia; Orthokeratolog; Meibomian gland; Meibomian scores; Miss meibomian; Break-up