pregnant women complicated with covid 19 a clinical analysis of 3 cases

• DOI: 10.3785/j.issn.1008-9292.2020.03.08
• Publication Date: 2020-03-17
• Authors: Hongliu Cai; Jifang Sheng; Jinxi Wang; Hongcui Cao; Yang Li; Xu Chen
• Keywords: Cesarean Section; SARS-CoV-2; Pneumonia, Viral; Pregnancy Outcome; COVID-19; Antiviral Agents; Oxygen; Betacoronavirus; Treatment Outcome; Pregnancy; Humans; Female; gamma-Globulins; Pregnancy Complications, Infectious; Coronavirus Infections; Glucocorticoids; Pandemics; Retrospective Studies

To analyze the clinical characteristics and pregnancy outcomes of pregnant women complicated with coronavirus disease 2019 (COVID-19).The clinical data of 3 pregnant women with COVID-19 admitted to the First Affiliated Hospital of Zhejiang University School of Medicine from January 19 to February 10, 2020 were retrospectively analyzed.There was one case in the first-trimester pregnancy (case 1), one in the second-trimester pregnancy (case 2) and one in third-trimester pregnancy (case 3). Cough, fever, fatigue, lung imaging changes were the main manifestations. The white cell count, lymphocyte percentage had no significantly changes in case 1 and case 3, while the levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), IL-6 and IL-10 elevated. The lymphocyte count and lymphocyte percentage decreased and the inflammatory indicators significantly increased in case 2. All patients were treated with antiviral, antitussive, oxygen inhalation; case 3 received glucocorticoids, case 2 with severe illness received glucocorticoids and additionally gamma globulin. All three cases were cured and discharged. Case 1 with early pregnancy chose to terminate pregnancy after discharge; case 2 chose to continue pregnancy without obstetric complications; and case 3 had cesarean section delivery due to abnormal fetal heart monitoring.The report shows that COVID-19 in pregnancy women could be cured with active treatment, and the maternal and fetal outcomes can be satisfactory.