Human papillomavirus DNA detection in cervical samples from women of reproductive age in Mogadishu, Somalia

• DOI: 10.3855/jidc.19982
• Publication Date: 2024-12-17T14:01:42Z
• Authors: Bashiru Garba; Maryan A Sh Nur; Maryam Adawe; Mohamed H Adam; Jamal H Mohamoud; Hassan A Dahie; Mohamed M Ahmed; Abdirahman K Mohamud; Sadio A Mohamed; Fartun AH Orey; Jihaan Hassan; Hodo A Asowe; Najib I Dirie
• Keywords: Dna testing

Introduction: Somalia is among the countries with a high burden of human papillomavirus (HPV) infection in Sub-Saharan Africa. In 2022, 660,000 infections are reported women globally, out which 350,000 died from disease. Most studies on HPV based cytologic analysis subjective and suboptimal assessment. The recent World Health Organization (WHO) guidelines for recommend DNA-based testing as better alternative to traditional pap smear test. Methodology: This study was undertaken determine prevalence preferred DNA assay cervical samples reproductive age Mogadishu, Somalia. detection carried using real-time quantitative polymerase chain reaction (RT-PCR) assays identify high-risk oncogenic HPV16, HPV18, other types. Results: Overall, 31.7% (60/189) were positive DNA. Out this, 19.6% risk-HPV (hrHPV), 13.8% 5.3% HPV18. Moreover, age, income education level found be significant risk factors infection. Conclusions: These results provide further proof that continues serious public health challenge progressing fatal cancer.