Influence of incision infection on coagulation and fibrinolysis and lymphedema after breast surgery

• DOI: 10.3877/cma.j.issn.1674-3946.2018.05.014
• Publication Date: 2018-10-26
• Authors: Yun Liang; Renfei Guo; Jing Zeng; Hongwang Lin; Xue Li
• Keywords: Radical mastectomy

Objective To investigate the influence of incision infection on coagulation and fibrinolysis lymphedema after breast surgery.

Methods From January 2016 to May 2018, clinical data 86 patients underwent radical mastectomy were retrospectively analyzed. 34 with postoperative divided into observation group 52 uninfected control group. Statistical analysis performed by using SPSS21.0 software. The indexes fibrinolysis, time occurrence upper limb lymphedema, parameters platelet level serum cytokines expressed as mean±standard deviation examined independent t test. incidence was χ2 test (P<0.05).

Results The PT、APTT in significantly lower than those group, D-D FIB higher non-infected significant difference (P<0. 05). infected that shorter (P<0.05). PDW、MPV PCT levels IL-4, IL-6, IL-10, TNF-α IFN-γ (P<0.05).

Conclusion Incision could lead elevated inflammatory factors, abnormal parameters, which are closely correlated patients.

Key words: Mastectomy, Radical; Infection; Lymphedema; Prothrombin Time