Primary breast myeloid sarcoma: A case report and literature review

• DOI: 10.3892/ol.2024.14804
• Publication Date: 2024-11-15T12:21:26Z
• Authors: Zhiying Zhang; Yibo Chen; Rui Zhang; Ming Liu
• Keywords: Myeloid sarcoma; Primary (astronomy)

Myeloid sarcoma (MS) is a rare extramedullary tumor originating from immature bone marrow cells. MS of the breast an extremely uncommon disease with non-specific clinical and radiological features. The present case report describes distinctive breast, which posed diagnostic challenges due to absence typical imaging characteristics at time presentation. patient was 58-year-old woman who presented mass. Further examination testing confirmed diagnosis in right metastases iliac, pubic ischial regions. Immunohistochemical analysis identified metastatic tumors distinguished by expression number markers, including Ki-67, myeloperoxidase cluster differentiation 43. underwent six cycles chemotherapy regimen comprising etoposide, methylprednisolone, cytarabine cisplatin, 28 (56 cGy each) consolidation radiotherapy. Extensive long-term follow-up revealed no further recurrence or metastasis. sarcomas typically manifest as palpable masses requiring imaging. However, rarity without any signs leukemia, its treatment are challenging. highlights importance maintaining high clinical, pathological standards when diagnosing this disease. Additionally, comprehensive review literature on provided. This necessity for clinicians consider patients presenting mass, facilitate appropriate prevent unnecessary procedures such mastectomies.