Microwave-Assisted Extraction of Fucoidan from Sargassum plagiophyllum and its Activities

• DOI: 10.3923/pjbs.2022.1008.1013
• Publication Date: 2024-03-07T05:48:51Z
• Authors: Dheasy Herawati; Esti Hendradi; Andi Hamim Zaidan; Pratiwi Pudjiastut
• Keywords: Fucoidan; Sargassum

<b>Background and Objective:</b> Fucoidan extract from the <i>Sargassum plagiophyllum </i>brown seaweed are renowned for its anticancer antibacterial activities. is one of ingredients <i>S. </i>that can be extracted by conventional methods new methods, which microwave assisted extraction (MAE). Research on fucoidan </i>was still limited. Thus, an advanced experiment how (MAE) was conducted in this study activities against <i>Escherichia coli </i>bacteria HeLa cancer cells were studied. <b>Materials Methods:</b> collected Gunung Kidul Coast Yogyakarta, Indonesia. plagiophyllum</i> acquired applying MAE method at 600 W 5 min using hydrochloric acid as a solvent. The cytotoxicity assays performed MTT assay agar plate diffusion respectively. <b>Results:</b> yield examined 9.90% (w/w), consisted 2.60% sulfate 2.33 mg 100 g<sup>1</sup> fucose. finding indicated that exhibits no action cell line 27.82 mL<sup>1</sup>. <b>Conclusion:</b> technique proven to support </i>successfully. Therefore, has have promise beneficial activity.