3D artificial polymeric scaffolds for stem cell growth fabricated by femtosecond laser

• DOI: 10.3952/lithjphys.50121
• Publication Date: 2010-04-10T18:22:28Z
• Authors: M. Malinauskas; P. Danilevičius; D. Baltriukienė; M. Rutkauskas; A. Žukauskas; Ž. Kairytė; G. Bičkauskaitė; V. Purlys; D. Paipulas; V. Bukelskienė; R. Gadonas
• Keywords: 0301 basic medicine; 03 medical and health sciences

Femtosecond Laser Induced Polymerization is an attractive direct writing technique for rapid three-dimensional (3D) micro and nanofabrication in diverse applications.Recently, it has been successfully applied 3D scaffold fabrication required biomedicine applications.However, there are still a lot of investigations to be done before can used practical applications tissue engineering or regenerative medicine.In this work, experimental results on production artificial polymeric scaffolds stem cell growth presented.Parameters (average laser power, sample scanning speed, developing conditions) microfabrication biocompatible photopolymers AKRE (AKRE37) ORMOSIL (SZ2080) experimentally determined.3D custom form size were microfabricated.Adult them was investigated order test their biocompatibility.The myogenic culture expansion compared the control same cells manufactured out commonly ORMOCER (Ormocore b59) Poly-Ethylen Glycol Di-Acrylate (PEG-DA-258).Preliminary show FLIP have potential proliferation experiments.These first steps transferring method from laboratory tests flexible manufacturing individual biodegradable polymers.