7-Methoxy-pyrrolo[1,2-a]quinolines via quinolinium N-ylides

• DOI: 10.3998/ark.5550190.0010.c21
• Publication Date: 2012-10-01T20:36:43Z
• Authors: Mino R. Caira; Emilian Georgescu; Florentina Georgescu; Marcel M. Popa; Florea Dumitraşcu
• Keywords: 01 natural sciences; 0104 chemical sciences

The pyrrolo[1,2-a]quinoline derivatives 4 and 6 were obtained by 1,3-dipolar cycloaddition of the quinolinium N-ylides in a one-pot three-component reaction under the assistance of the solvent which acts as both reaction medium and HBr scavenger. The one-pot three-component reaction could not be extended to compounds 8a-c which were obtained in two steps. The compounds were characterized by NMR and the cycloadduct 4e was investigated by X-ray analysis.