Impact of Optimal Stent Expansion on Late Outcomes after Sirolimus-Eluting Stent Implantation: An Intravascular Ultrasound Study

• DOI: 10.4070/kcj.2007.37.6.244
• Publication Date: 2009-10-01T04:22:01Z
• Authors: Chang-Wook Nam; Kwon-Bae Kim; Seung-Ho Hur; Yun-Kyeong Cho; Hyung Seop Kim; Seong-Wook Han; Yoon-Nyun Kim; In-Sung Chung; Young-Soo Lee; Kee-Sik Kim
• Keywords: Intravascular Ultrasound; Sirolimus

Background and Objectives:Sirolimus-eluting stents (SESs) have a considerably lower optimal minimal stent area (MSA) threshold compared to bare metal (BMSs). In the SIRIUS IVUS sub study, absolute expansion (OSE) of SESs was described as ≥5.0 mm. The purpose this study evaluate impact OSE on long-term outcomes following SES implantation using criteria. Subjects Methods:The included 157 patients (BMS: 57; SES; 100), who underwent 6-month follow-up angiography 18-month clinical after or drug-eluting (DES) implantation. According measurement criteria, were divided into two groups: non-OSE. criteria for MSA ≥6.5 mm BMS Results:Angiographic binary restenosis higher in non-OSE than group with (33.3% vs. 11.4%; p<0.039), but rates similar between groups (4.5% 3.2%; p=1.00). With BMS, MACE 5.7% 30% group, respectively (p=0.017). However, SES, (OSE 3.2% 4.5%, Conclusion: After implantation, there no significant differences late relation achievement OSE. A variety related factors should be considered better DES Therefore, concept era DESs might need revisited. (Korean Circulation J 2007;37:244-250)