Primary Diffuse Large B-Cell Lymphoma of the Ascending Colon

• DOI: 10.4081/rt.2013.e23
• Publication Date: 2013-06-07T10:23:19Z
• Authors: Aram Barbaryan; Alaa M. Ali; Shawn G. Kwatra; Raya Saba; Suartcha Prueksar...; Nasir Hussain; Aibek E. Mirrakhimov; Natalya Vladimirskiy; Teresita Zdunek; Alan D. Gilman
• Keywords: 03 medical and health sciences; 0302 clinical medicine; lymphoma, gastrointestinal lymphoma, hypercalcemia, abdominal mass, diffuse large B-cell lymphoma; Neoplasms. Tumors. Oncology. Including cancer and carcinogens; Case Report; RC254-282; 3. Good health

Primary colorectal lymphoma is a rare malignancy accounting for 3% of all gastrointestinal lymphomas and 0.1-0.5% of all colorectal malignancies. Among primary colorectal lymphomas, the most common histological subtype of colorectal lymphoma is diffuse large B-cell lymphoma. We report a case of an 84-year old Caucasian female who was admitted to the hospital because of a 2 days history of altered mental status. In the emergency department the patient was found to have acute kidney injury and hypercalcemia. On physical examination a large lower quadrant abdominal mass was palpated. Computed tomography scan of abdomen confirmed the presence of a mass along the cecum and proximal ascending colon. Colonoscopy showed a large ulcerated mass and biopsy was consistent with diffuse large B-cell lymphoma. The patient underwent colectomy but refused to receive chemotherapy.