Coexistence of autoimmune diseases and autoantibodies in patients with myasthenia gravis

• DOI: 10.4103/0028-3886.173638
• Publication Date: 2016-04-27T12:20:32Z
• Authors: Sibel Tamer; HafizeNalan Gokce...; Elif Gokcal; TahirKurtulus Yoldas
• Keywords: Anti-thyroid autoantibodies

Background: In this study, we assessed 75 patients with myasthenia gravis (MG) for coexistent autoimmune diseases (ADs) and the characteristic autoantibodies that are associated most relevant forms of ADs.Methods: The demographic clinical characteristics were recorded. all patients, thyroid function tests, autoantibodies, other studied. diagnosis disease (AITD) was made based on features, physical examination, laboratory findings. diagnoses rheumatoid arthritis (RA) systemic lupus erythematosus (SLE) in accordance revised criteria American College Rheumatology. presence ADs also recorded which whether or not patient already had a ADs; or, it detected during period study findings and/or abnormalities.Results: Thirty-nine (52%) autoantibody positivity their sera. Thyroid antinuclear antibodies main detected. twenty one these AD could be confirmed. Eighteen (24%) confirmed coexisting AD. These included AITD (16%), RA (4%), SLE (2.6%), Lambert–Eaton myasthenic syndrome (1.3%). ten been established before development MG; 8 those who newly diagnosed course management MG.Conclusions: MG has an increased frequency ADs. Autoantibodies can found without any Clinical attention towards is especially needed follow-up MG.