Spectral domain optical coherence tomography morphology in optic disc pit associated maculopathy

• DOI: 10.4103/0301-4738.138184
• Publication Date: 2014-08-13T16:38:08Z
• Authors: Zofia Michalewska; Janusz Michalewski; Jerzy Nawrocki
• Keywords: Adult; Male; intravitreal; squint; Time Factors; ophthalmic drug delivery; Optic Disk; Visual Acuity; nanosponges; neovascular age related macular degeneration; Hydrophillic nanogels; 03 medical and health sciences; 0302 clinical medicine; systematic review; Maculopathy; Optic Nerve Diseases; Adult strabismus; Humans; Macula Lutea; psychosocial impact; systematic review of reviews; Retinal Degeneration; systemic; RE1-994; Bevacizumab; solid lipid nanoparticles; Ophthalmology; spectral domain optical coherence tomography; quality of life; personality; optic pit; Original Article; Female; Tomography, Optical Coherence; Follow-Up Studies

Our purpose was to study the clinical manifestation and course of optic pit maculopathy using Spectral Domain Optical Coherence Tomography (SD- OCT) images.We used SD-OCT to examine 20 eyes of 19 patients with a macular detachment in combination with an optic.We observed five different fovea appearances in regard to fluid localization. In five eyes, we recorded changes in the fluid distribution with SD-OCT. In 17/20 eyes, we noted a communication between the perineural and subretinal and/or intraretinal space at the margin of the optic disc.3-dimensional SD-OCT (3D-SDOCT) scans revealed a three-fold connection, between subretinal and intraretinal space, perineural space, and the vitreous cavity. Therefore, we suppose that intraretinal or subretinal fluid in optic pit maculopathy may have both a vitreous and cerebrospinal origin. A membrane, covering the optic nerve was noted in 14 cases. Even if it seems intact in some B-scans, it is not complete in others several micrometers apart. Additionally, we observed fluid accumulation below the margin of the optic disc and hyperreflective porous tissue in the optic disc excavation. Those findings do not influence the course of maculopathy.