Atypical presentations of eosinophilic fasciitis

• DOI: 10.4103/0378-6323.171010
• Publication Date: 2015-12-03T10:39:48Z
• Authors: Andac Salman; Tulin Ergun; Dilek Seckin; EsraSarac Ocak; AyseDeniz Yucelten; Haner Direskeneli; Cuyan Demirkesen; Gazanfer Ekinci; Mahmut Bayik
• Keywords: Male; LICHEN-SCLEROSUS; Adolescent; morphea; FEATURES; DIAGNOSIS; Risk Assessment; DISEASE; Sampling Studies; Diagnosis, Differential; lichen sclerosus; Scleroderma, Localized; 03 medical and health sciences; MORPHEA; 0302 clinical medicine; CHILD; Adrenal Cortex Hormones; sclerosing disorders; Eosinophilia; magnetic resonance imaging; Humans; Fasciitis; PUVA Therapy; SPECTRUM; Echo-Planar Imaging; Biopsy, Needle; Eosinophilic fasciitis; Middle Aged; Immunohistochemistry; 3. Good health; Lichen Sclerosus et Atrophicus; Treatment Outcome; OF-THE-LITERATURE; Female; MRI; Follow-Up Studies

Eosinophilic fasciitis is an uncommon connective tissue disease that may mimic and overlap with other sclerosing disorders such as morphea and lichen sclerosus. Herein, we report four patients (two men and two women, aged 16-64 yeas) with eosinophilic fasciitis. There was overlap with both morphea and lichen sclerosus in 2 patients and with morphoea alone in 1 patient. Magnetic resonance imaging (MRI) was used for diagnosis in three patients and for assessing treatment response in one patient. Eosinophilic fasciitis may co-exist with morhoea and lichen sclerosus. In view of the overlapping clinical and histopathological features of these disorders, MRI may be helful in delineating the conditions by detecting involvement of fascia.