Posttesticular sperm maturation, infertility, and hypercholesterolemia

• DOI: 10.4103/1008-682x.155536
• Publication Date: 2015-04-21T06:05:25Z
• Authors: JoëlR Drevet; Marjorie Whitfield; Xavier Pollet-Vil...; Rachel Levy; Fabrice Saez
• Keywords: Dyslipidemia

Cholesterol is a key molecule in the mammalian physiology of especial particular importance for reproductive system as it common precursor steroid hormone synthesis. also recognized modulator sperm functions, not only at level gametogenesis. homeostasis regulation crucial posttesticular maturation, and imbalanced cholesterol levels may particularly affect these events. Metabolic lipid disorders (dyslipidemia) male fertility but are most time studied from angle endocrine/testicular consequences. This review will focus on deleterious effects dyslipidemia, i.e., hypercholesterolemia, maturation spermatozoa.