Low Dose and the Conventional Dose Of 0.5% Hyperbaric Bupivacaine Produce Comparable Outcomes in the Lower Segment Caesarean Section. An Observational Study

• DOI: 10.4103/aam.aam_131_21
• Publication Date: 2022-11-15T12:16:01Z
• Authors: Sudhir Kumar; Neeta Santha
• Keywords: Cesarean Section; Bupivacaine; 3. Good health; 03 medical and health sciences; 0302 clinical medicine; Pregnancy; Humans; Anesthesia, Obstetrical; Original Article; Female; Prospective Studies; Anesthetics, Local

Background: Spinal anesthesia with 0.5% hyperbaric bupivacaine is an approved technique for lower segment cesarean sections. This study compared two different hyperbaric bupivacaine doses for spinal anesthesia in the lower segment cesarean section. We hypothesized that low-dose spinal anesthesia had similar outcomes as conventional doses of bupivacaine.

Methods: This was a comparative observational study involving seventy healthy parturients who were posted for elective cesarean section. Patients were supposed to receive 0.5% hyperbaric bupivacaine and were divided into groups, low dose (LB-1.8 ml) and conventional-dose (HB-2.2 ml) group. The extent of motor blockade, sensory blockade, hemodynamic effects, visual analog scale for pain, and patient satisfaction were measured. The data were analyzed using the median and interquartile range for all parameters. A statistical package SSPS version 25.0 was used to do the analysis.

Results: Hemodynamic stability was well maintained in both groups. Almost 100% of the patients in both groups achieved a grade 3 motor blockade in 8 min. T6 level of sensory blockade was achieved in 6 min by 100% of the patients. The low-dose group made a faster recovery compared with the high-dose group.

Conclusion: Low-dose spinal anesthesia can cause similar hemodynamic and analgesic effects as the conventional-dose group. The only benefit of low dose spinal as compared with conventional-dose group was faster recovery from the anesthetic effects.