Clinicomicrobiological profile of endophthalmitis: A 10 year experience in a Tertiary Care Center in North India

• DOI: 10.4103/ijpm.ijpm_794_15
• Publication Date: 2017-06-19T10:43:03Z
• Authors: Meenakshi Wadhwani; Gita Satpathy; Niranjan Nayak; Pradeep Venkwatesh; Atul Kumar; Yograj Sharma; Vishnu Sreenivas
• Keywords: Klebsiella

<b>Purpose:</b> To determine the clinicomicrobiological profile of infectious agents and their antibiotic susceptibility in different type endophthalmitis. <b>Methods:</b> A retrospective review clinical microbiological records from January 2001 to December 2010, was performed 1110 patients diagnosed with endophthalmitis (postoperative, posttraumatic, endogenous post keratitis) record demographic details, presentations; isolated antimicrobial sensitivity pattern. Antimicrobial testing for various culture positive isolates (bacterial/fungal) by disc diffusion technique. <b>Results:</b> Out intra-ocular specimens processed, 384 (34.6%) were bacteria. S epidermidis most predominant isolate accounting 42.7% all bacteria obtained, followed Pseudomonas aeruginosa (24.5%). Besides Pseudomonas, Acinetobacter spp. next common gram negative bacilli detected (8.3%) Klebsiella, E. coli, Enterobacter Alkaligenes 2.6%, 0.8%, 0.8% 0.5% cases respectively. The fungal species Aspergillus spp., 36.1%, Fusarium 26.4% cases. Overall pattern our study showed that susceptible glycopeptides like vancomycin (80-100%) fluoroquinolones (87-91%). organisms Klebsiella towards ranged between 61% - 82%. <b>Conclusion:</b> postoperative posttraumatic endophthalmitis, bacterial endophthalmitisAmongst fungi organism.