Myasthenic Crisis in a Child: Successful Recovery after Early Identification and Intervention

• DOI: 10.4103/ipcares.ipcares_237_23
• Publication Date: 2024-05-13T13:00:25Z
• Authors: Ishmeet Kaur Jaggi; Pooja Dewan; Deepika Harit; Jaya Shankar Kaushik; Mukesh Yadav
• Keywords: Trismus; Plasmapheresis

Background: Juvenile myasthenia gravis (MG) is a rare autoimmune neuromuscular disorder and has varied presentation in childhood making it diagnostic challenge. Clinical Description: An 8-year-old girl presented to the pediatric emergency with multiple episodes of falling, drooling saliva, dysphagia, bilateral ptosis. Within few hours admission, she had acute deterioration, developed respiratory failure, was put on ventilatory support. Management Outcome: A myasthenic crisis suspected neostigmine challenge test done. She managed atropine, neostigmine, intravenous immunoglobulin, supportive care. Subsequently, achieved complete remission steroids, physostigmine, oral mycophenolate mofetil over next 6 weeks. Conclusion: MG may rarely be cause generalized muscular weakness. strong suspicion must kept case sudden deterioration involving bulbar muscles, patient neurologic Early intervention this condition can lifesaving.