Effect of Percutaneous Coronary Intervention on Diastolic Function in Coronary Artery Disease

• DOI: 10.4103/jcecho.jcecho_128_20
• Publication Date: 2024-06-01T19:51:08Z
• Authors: Puneet Aggarwal; Santosh Kumar Sinha; Rishabh Marwah; Ranjit Kumar Nath; Bhagya Narayan Pa...; Ajay Pratap Singh

Left ventricle (LV) diastolic dysfunction is often present in patients with significant coronary artery disease (CAD), even the absence of regional or global LV systolic dysfunction. It has been suggested that abnormalities function may actually precede dysfunction, and therefore, serve as an early sensitive marker ischemia. This study aims to find improvement after percutaneous intervention (PCI) stable unstable angina.In this single-center hospital-based study, we enrolled 309 either CAD normal who underwent successful PCI. Two-dimensional transthoracic echocardiography was performed at baseline (before PCI) repeated 48 h parameters were compared before PCI using paired samples t-test results.Mean age population 56.65 ± 9.65 years. Majority male (63%). There increase mitral E-wave velocity (68.39 17.52 cm/s vs. 71.64 18.23 cm/s), E/A ratio (0.85 0.29 0.89 0.32), annular motion (e') (7.02 8.45 0.86 cm/s) following (P < 0.0001). atrial volume index (22.53 4.43 20.81 4.14), tricuspid jet (0.91 0.57 m/s 0.76 0.67 m/s), E/e' (10.03 3.5 8.62 2.61) decreased significantly 0.001).This suggests filling pattern modified Improvement impaired relaxation appears be most likely explanation for these changes. potential therapeutic target improve CAD.