Molecular characterization of group A rotavirus (RVA) strains detected in bovine and porcine species: Circulation of unusual rotavirus strains. A study from western, India

• DOI: 10.4149/av_2019_113
• Publication Date: 2019-03-18T08:15:18Z
• Authors: V. S. TATTE; M. JADHAV; V. C. INGLE; V. GOPALKRISHNA
• Keywords: Reassortment; Group A

Group A rotaviruses (RVA) are considered as important causative agents of diarrhea in both human and animal species. Fecal specimens (n = 300) were collected from diarrheic healthy animals during the year 2009 farms Nagpur (Maharashtra), Western India. RVA antigen was detected by ELISA 3.1-25% 72% bovine porcine species, respectively. Genotyping based on VP6, VP7 VP4 RVA-positive samples showed predominance genotype I-1 (63%) I-2 (37%), G4 (45.5%) G10 (27.3%) genotypes, P[6] (72.7%) P[8] (18.1%) Other RV genotypes such G1(4.5%), G2(9.1%), G3(4.5%) mixed infections (9.1%) at low level. Predominance unusual G-P combinations (9/23, 39.1%) observed. Circulation G2P[8] with G1, G3, P[8], P[6]) reported species for first time In conclusion present study highlights circulation VP6 genogroup specificities strains indicative possible interspecies transmission reassortment events The further warrants utmost need surveillance studies across country to understand role genetic reservoirs emergence pathogenic humans. Keywords: rotaviruses; genotypes; types; animals.