Helicobacter pylori can be related to carotid intima-media thickness, epicardial adipose tissue thickness and serum neutrophil gelatinase-associated lipocalin (NGAL) levels

• DOI: 10.4149/bll_2018_057
• Publication Date: 2018-05-11T10:41:09Z
• Authors: Z. Karadag; T. Sehitoglu; M. C. Cure; H. Rakici; M. A. Ayvaz; R. Bedir; B. Kizilkaya; O. Z. Şahin; E. Cure
• Keywords: Subclinical infection; Intima-media thickness; Helicobacter

BACKGROUND: Helicobacter pylori (HP) affects the cardiovascular system.Our aim in this study was to evaluate, whether an infection with HP causes subclinical atherosclerosis.METHODS: We included 90 patients dyspeptic symptoms study.The underwent upper gastrointestinal endoscopy and biopsies were taken.The grouped according histopathologic examination, as negative (n = 21), positive (+) 23), (++) 22), (+++), 24).RESULTS: The neutrophilic gelatinase-associated lipocalin (NGAL) high-sensitive C-reactive protein (hs-CRP) levels carotid intima-media thickness (cIMT) epicardial adipose tissue (EAT) group signifi cantly lower than NGAL (p < 0.001) hs-CRP cIMT 0.008) EAT (+++) group.There a strong correlation between serum levels, thickness.CONCLUSION: HP-infection can lead atherosclerosis via chronic infl ammation.The higher activity of infection, acceleration (Tab.3, Fig. 2, Ref. 46).