Correlation between gastritis cystica profunda and the risk of lymph node metastasis in early gastric cancer

• DOI: 10.4149/neo_2022_220314n281
• Publication Date: 2022-12-30T13:25:52Z
• Authors: Jia-Jia WU; Yu-Qing CHENG; Hao-Jun YANG; Min LIN
• Keywords: Lymphovascular invasion; Univariate analysis

In early gastric cancer (EGC) patients, lymph node metastasis (LNM) risk assessment is particularly important for the selection of surgical methods.In this study, we investigated correlation between gastritis cystica profunda (GCP) and LNM in EGC.From January 2014 to December 2019, EGC patients who underwent curative radical gastrectomy were enrolled study.The clinicopathological features analyzed, GCP was assessed.Data 180 17.8% (32/180) had LNM.The incidence 2.6% GCP-positive group 21.8% GCP-negative group.Univariate analysis revealed that GCP, depth tumor invasion, lymphovascular invasion factors patients.Multiple regression showed associated with (OR=0.097,0.121, 0.100, p<0.05).The curve fitting results there a negative EGC, which consistent different sites, size, ulceration, differentiation types, no significant interaction found among these (p range 0.224-0.717).GCP closely related EGC.Preoperative whether combined beneficial LNM.